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Resident Evil Requiem is finally here, making it a great time to brush up on all that’s happened across the Resident Evil series’ 30-year history. This is especially true as Resident Evil Requiem looks to combine a bunch of different story threads across both mainline and spin-off titles in the series. For those that are jumping into the franchise for the first time, or for those who need a refresher on key plot details, here’s everything you need to know before playing Resident Evil Requiem. Oh, and as you might have suspected, plenty of spoilers lie ahead, so read at your own discretion.
In the mid- 1960s, a group of scientists led by Oswell E. Spencer discovered the Progenitor virus, which they believed could be used to essentially speed up humanity’s evolution. In order to fund their research, they agreed to develop new strains of the virus for the U.S. military to be used as bioweapons, as one of the biggest hurdles in utilizing the Progenitor virus to evolve humanity was that it had a high mortality rate. Thus, the Umbrella Corporation was born, as well as a litany of new strains of Progenitor. One of these strains, of course, was

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